Jen Kirkman is from LA. Self-Help is her first release, and it was recorded at the left coast branch of the Upright Citizens Brigade. Normally, invoking UCB to me causes simultaneous visions of improv comedy competitions and companion desires to imitate Oedipus and VanGogh, but rest assured that this is not improv comedy. This 40 minutes is the only stuff I've heard from her, but from this set Kirkman reminds me a lot of Morgan Murphy with a strong Louis C.K turn. Which is to say that it's pretty damn good. I'd check it out.
In tracking down label info for this, I have discovered that Self Help is both a couple years old and on my new favorite comedy label A Special Thing. Get it here, anyway.